Several laboratory tests are available to detect outbreaks of canine influenza.
CIV infection should be suspected in dogs with respiratory signs.
Serology to detect CIV-specific antibodies is the most reliable diagnostic test for confirmation of CIV infection.
- This testing should be performed in conjunction with other tests to confirm canine influenza.
- The timing of serum sample collection is also critical. CIV-specific antibodies can be detected in a hemagglutination inhibition assay as early as 7 days postinfection; however, reliable detection occurs after 10 days of clinical signs.2,24
Therefore, it is important to note that a negative antibody titer for serum samples collected before day 10 does not rule out CIV infection.2,4 In addition, because the presence of antibodies only indicates exposure but not necessarily active infection, it is necessary to compare an acute titer with a titer taken at least 2 weeks later (a convalescent titer) to confirm a four-fold or greater rise in antibody titer (seroconversion) in order to prove that there was a recent active infection.2,4
Serum samples can be submitted to:2,4